It is the first Grand Slam title for Aryna Sabalenka.
19-year-old Bianca Andreescu of Canada beat US Open Serena Williams of the United States 6-3, 7-5 in the singles event.
In the men's singles Spain's Rafael Nadal won the US Open for the fourth time defeating Daniil Medvedev of Russia 7-5, 6-3, 5-7, 4-6, 6-4 in almost five hours.
The men's doubles event was won by Colombia's Juan Sebastian Cabal and Robert Farah who outlasted the Argentinean-Spanish duet of Horacio Zeballos and Marcel Granollers 6-4, 7-5.